SCHEMBL5282483

SCHEMBL5282483

CCc1ccc(OCCOc2cc(C)ccc2C)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.50
TDP1 Q9NUW8 4/20 0.44
PPARG P37231 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
CYP2C9 P11712 2/20 0.44
TTR P02766 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C8 P10632 1/20 0.44
CHRM1 P11229 1/20 0.44
ADRA1A P35348 1/20 0.44
HTR2B P41595 1/20 0.44
PPARA Q07869 1/20 0.44
SLCO1B3 Q9NPD5 1/20 0.44
CISD1 Q9NZ45 1/20 0.44
SLCO1B1 Q9Y6L6 1/20 0.44
GAA P10253 1/20 0.44
LMNA P02545 3/20 0.44
ALDH1A1 P00352 3/20 0.44
MAPT P10636 1/20 0.44
HPGD P15428 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3763431 0.88 TSHR (0.57) TSHRTDP1PPARGSMN1; SMN2CYP2C9
SCHEMBL5293729 0.87 SMN1; SMN2 (0.47) TSHRTDP1PPARGSMN1; SMN2PPARA
SCHEMBL5294667 0.82 ALDH1A1 (0.55) SMN1; SMN2LMNAALDH1A1MAPTHPGD
SCHEMBL5929495 0.82 TSHR (0.67) TSHRTDP1PPARGSMN1; SMN2CYP2C9
SCHEMBL10705816 0.82 TSHR (0.55) TSHRTDP1PPARGSMN1; SMN2CYP2C9
SCHEMBL5297810 0.81 TSHR (0.54) TSHRTDP1PPARGSMN1; SMN2CYP2C9
SCHEMBL15869720 0.81 TSHR (0.58) TSHRTDP1PPARGSMN1; SMN2CYP2C9
SCHEMBL14228536 0.81 DRD2 (0.48) TDP1PPARGCYP1A2PPARAALDH1A1
SCHEMBL5281663 0.80 L3MBTL1 (0.61) TSHRTDP1PPARGSMN1; SMN2CYP1A2
SCHEMBL5279217 0.79 TDP1 (0.50) TSHRTDP1PPARGSMN1; SMN2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
US-20060293181-A1 Thermal recording materials and methods of making and using the same NASHUA CORPORATION 2006-12-28 US disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed
US-RE36321-E INCLUDING DIARYL DIETHER COMPOUND KANSAKI PAPER MANUFACTURING CO., LTD. (JP) 1999-09-28 US disclosed
EP-0141170-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-05-13 EP disclosed
US-4531140-A Heat-sensitive recording material Kansaki Paper Manufacturing Co. Ltd. (JP) 1985-07-23 US disclosed
EP-0141170-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-05-15 EP disclosed