SCHEMBL5282486

SCHEMBL5282486

CC(C)(C)c1ccc(OCCOc2ccc(Cl)cc2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.53
POLB P06746 3/20 0.50
HRH3 Q9Y5N1 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
LMNA P02545 2/20 0.50
RAB9A P51151 2/20 0.50
ATM Q13315 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
APP P05067 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NPC1 O15118 1/20 0.46
MITF O75030 1/20 0.46
TP53 P04637 1/20 0.46
MAPT P10636 1/20 0.46
DRD2 P14416 1/20 0.46
DRD4 P21917 1/20 0.46
DRD3 P35462 1/20 0.46
MAOB P27338 2/20 0.45
KCNH2 Q12809 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13439793 0.83 APP (0.70) POLBLMNARAB9AATML3MBTL1
SCHEMBL20234326 0.83 HRH3 (0.61) KDM4EPOLBHRH3SMN1; SMN2LMNA
SCHEMBL22248702 0.83 HRH3 (0.62) KDM4EPOLBHRH3SMN1; SMN2LMNA
SCHEMBL1345118 0.82 MAOB (0.57) HRH3SMN1; SMN2RAB9AAPPNPC1
SCHEMBL11596113 0.82 PPARA (0.51) KDM4EPOLBSMN1; SMN2RAB9AMEN1
SCHEMBL1535647 0.82 KDM4E (0.54) KDM4EPOLBHRH3SMN1; SMN2LMNA
SCHEMBL5285127 0.82 ALDH1A1 (0.57) KDM4EPOLBHRH3SMN1; SMN2LMNA
SCHEMBL5282382 0.82 TSHR (0.62) KDM4EPOLBHRH3SMN1; SMN2LMNA
SCHEMBL7415609 0.82 HRH3 (0.56) KDM4EPOLBHRH3SMN1; SMN2LMNA
SCHEMBL3807523 0.82 RAB9A (0.59) KDM4EPOLBHRH3SMN1; SMN2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006138653-A9 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORP (US) 2007-03-01 WO disclosed
US-20060293181-A1 Thermal recording materials and methods of making and using the same NASHUA CORPORATION 2006-12-28 US disclosed
WO-2006138653-A1 THERMAL RECORDING MATERIALS AND METHODS OF MAKING AND USING THE SAME NASHUA CORPORATION (US) 2006-12-28 WO disclosed
US-RE36321-E INCLUDING DIARYL DIETHER COMPOUND KANSAKI PAPER MANUFACTURING CO., LTD. (JP) 1999-09-28 US disclosed
EP-0141170-B1 HEAT-SENSITIVE RECORDING MATERIAL KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1987-05-13 EP disclosed
US-4659643-A A PHENOXY COMPOUND KANZAKI PAPER MANUFACTURING CO. LTD. (JP) 1987-04-21 US disclosed
US-4531140-A Heat-sensitive recording material Kansaki Paper Manufacturing Co. Ltd. (JP) 1985-07-23 US disclosed
EP-0141170-A2 Heat-sensitive recording material KANZAKI PAPER MANUFACTURING COMPANY LIMITED (JP) 1985-05-15 EP disclosed