Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | NPY2R | P49146 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282389 | 0.90 | ALDH1A1 (0.53) | LMNAALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL5284001 | 0.87 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1MAPK1MAPTSMN1; SMN2 | |
| SCHEMBL29169367 | 0.73 | L3MBTL1 (0.79) | LMNAALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL9880917 | 0.73 | L3MBTL1 (0.79) | LMNAALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL5287640 | 0.73 | POLB (0.41) | LMNAALDH1A1MAPK1KDM4EKMT2A | |
| SCHEMBL13748438 | 0.73 | NPC1 (0.62) | LMNAALDH1A1L3MBTL1MAPK1KMT2A | |
| Toluene SCHEMBL27497137 | 0.71 | ALDH1A1 (0.59) | LMNAALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL21235487 | 0.71 | ALDH1A1 (0.60) | LMNAALDH1A1L3MBTL1MAPK1KDM4E | |
| E1501 SCHEMBL28313206 | 0.71 | ALDH1A1 (0.85) | LMNAALDH1A1L3MBTL1MAPK1KMT2A | |
| SCHEMBL6647983 | 0.71 | ALDH1A1 (0.60) | LMNAALDH1A1L3MBTL1MAPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |