Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5291028 | 0.80 | PKM (0.47) | KMT2AALDH1A1MAPTTSHRSMN1; SMN2 | |
| SCHEMBL5282389 | 0.79 | ALDH1A1 (0.53) | POLBMEN1KMT2AALDH1A1MAPK1 | |
| SCHEMBL27922939 | 0.76 | POLB (0.39) | POLBMEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL2255789 | 0.73 | PNMT (0.42) | POLBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL5282555 | 0.73 | LMNA (0.49) | KMT2AALDH1A1HTTMAPK1MAPT | |
| SCHEMBL27547241 | 0.71 | MEN1 (0.41) | POLBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL10769337 | 0.71 | PKM (0.31) | KMT2A | |
| SCHEMBL20926920 | 0.70 | GAA (0.42) | POLBMEN1KMT2AALDH1A1HTT | |
| SCHEMBL12303003 | 0.69 | PNMT (0.38) | POLBMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL11316708 | 0.69 | MEN1 (0.40) | POLBMEN1KMT2AALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-RE35281-E | ANTIDIABETIC AGENTS | WAKAMOTO PHARMACEUTICAL CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |