Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 4/20 | 0.56 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | XIAP | P98170 | 1/20 | 0.46 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7205029 | 1.00 | SLC7A5 (0.56) | SLC7A5ESR1ESR2CYP1A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL20422673 | 0.98 | SLC7A5 (0.54) | SLC7A5ESR1ESR2CYP1A2HSD17B10 | |
| Hydrochloric Acid SCHEMBL20422675 | 0.98 | SLC7A5 (0.54) | SLC7A5ESR1ESR2CYP1A2HSD17B10 | |
| SCHEMBL15360000 | 0.83 | CYP1A2 (0.49) | SLC7A5CYP1A2HSD17B10PTGS1PKM | |
| SCHEMBL13957329 | 0.81 | CYP1A2 (0.47) | SLC7A5CYP1A2HSD17B10PTGS1PKM | |
| SCHEMBL12128833 | 0.81 | CYP1A2 (0.47) | SLC7A5CYP1A2HSD17B10PTGS1PKM | |
| SCHEMBL4208145 | 0.81 | CYP1A2 (0.47) | SLC7A5CYP1A2HSD17B10PTGS1PKM | |
| SCHEMBL8168327 | 0.81 | ESR1 (0.49) | SLC7A5ESR1ESR2ALDH1A1KIF11 | |
| Hydrochloric Acid SCHEMBL25217806 | 0.80 | CYP1A2 (0.46) | SLC7A5CYP1A2HSD17B10PTGS1PKM | |
| SCHEMBL31369948 | 0.80 | NNMT (0.47) | SLC7A5CYP1A2HSD17B10PTGS1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | claimed |
| WO-2020194563-A1 | AGENT FOR PREVENTING OR IMPROVING SYMPTOMS OR DISEASE CAUSED BY PHENOLS | 国立大学法人東北大学 | 2020-10-01 | — | — | WO | disclosed |
| US-20190309289-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10370654-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. (US) | 2019-08-06 | — | — | US | disclosed |
| US-20180320170-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2018-11-08 | — | — | US | disclosed |
| US-10000555-B2 | Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus | SEATTLE GENETICS, INC. (US) | 2018-06-19 | — | — | US | disclosed |
| US-9944925-B2 | Processes and host cells for genome, pathway, and biomolecular engineering | ENEVOLV, INC. | 2018-04-17 | — | — | US | disclosed |
| US-20160186168-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. | 2016-06-30 | — | — | US | disclosed |
| EP-3027754-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | enEvolv, Inc. (US) | 2016-06-08 | — | — | EP | disclosed |
| WO-2015017866-A1 | PROCESSES AND HOST CELLS FOR GENOME, PATHWAY, AND BIOMOLECULAR ENGINEERING | ENEVOLV, INC. (US) | 2015-02-05 | — | — | WO | disclosed |
| US-5760237-A | Synthesis of l-azatyrosine using pseudoephedrine as a chiral auxiliary | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 1998-06-02 | — | — | US | disclosed |
| US-5658885-A | OLIGOPEPTIDES; ANTICOAGULANTS; ENZYME INHIBITORS; THROMBIN | THE DUPONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-19 | — | — | US | disclosed |
| EP-0787010-A1 | AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1997-08-06 | — | — | EP | disclosed |
| EP-0737691-A1 | Bombesin analogs | BIOMEASURE, INC. (US) | 1996-10-16 | — | — | EP | disclosed |
| WO-1996012499-A1 | AMIDINO AND GUANIDINO SUBSTITUTED INHIBITORS OF TRYPSIN-LIKE ENZYMES | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-05-02 | — | — | WO | disclosed |
| EP-0606464-A4 | PEPTIDES CAPABLE OF CONTROLLING ACROSOME REACTION. | OREGON MEDICAL RES FOUND (US) | 1995-10-25 | — | — | EP | disclosed |
| US-5439884-A | Applying a polypeptide in vitro to stimulate the artificial insemination | OREGON REGIONAL PRIMATE RESEARCH CENTER (US) | 1995-08-08 | — | — | US | disclosed |
| EP-0606464-A1 | PEPTIDES CAPABLE OF CONTROLLING ACROSOME REACTION | MEDICAL RESEARCH FOUNDATION OF OREGON (US) | 1994-07-20 | — | — | EP | disclosed |
| WO-1994002018-A1 | PEPTIDES CAPABLE OF CONTROLLING ACROSOME REACTION | THE MEDICAL RESEARCH FOUNDATION OF OREGON (US) | 1994-02-03 | — | — | WO | disclosed |
| EP-0313094-A2 | Anticancer agent and reagent for obtaining revertants | MEIJI SEIKA KAISHA LTD. (JP) | 1989-04-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000555-B2 | Monomethylvaline compounds having phenylalanine side-chain modification at the C-terminus | PTMS, MMAB, DNPEP | SLC7A5 54/4885ESR1 4145/4885ESR2 3945/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.