SCHEMBL7205029

SCHEMBL7205029

N[C@@H](Cc1ccc(O)cn1)C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 4/20 0.56
ESR1 P03372 1/20 0.50
ESR2 Q92731 1/20 0.50
CYP1A2 P05177 1/20 0.49
HSD17B10 Q99714 4/20 0.46
PTGS1 P23219 2/20 0.46
PKM P14618 2/20 0.46
ALPI P09923 1/20 0.46
XIAP P98170 1/20 0.46
GRIA2 P42262 1/20 0.45
KDM4E B2RXH2 3/20 0.44
ALOX15 P16050 3/20 0.44
USP2 O75604 3/20 0.44
ADORA3 P0DMS8 2/20 0.44
HTR2A P28223 2/20 0.44
RECQL P46063 2/20 0.44
HIF1A Q16665 2/20 0.44
TDP1 Q9NUW8 2/20 0.44
EGFR P00533 1/20 0.44
LCK P06239 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5283089 1.00 SLC7A5 (0.56) SLC7A5ESR1ESR2CYP1A2HSD17B10
Hydrochloric Acid SCHEMBL20422673 0.98 SLC7A5 (0.54) SLC7A5ESR1ESR2CYP1A2HSD17B10
Hydrochloric Acid SCHEMBL20422675 0.98 SLC7A5 (0.54) SLC7A5ESR1ESR2CYP1A2HSD17B10
SCHEMBL15360000 0.83 CYP1A2 (0.49) SLC7A5CYP1A2HSD17B10PTGS1PKM
SCHEMBL13957329 0.81 CYP1A2 (0.47) SLC7A5CYP1A2HSD17B10PTGS1PKM
SCHEMBL12128833 0.81 CYP1A2 (0.47) SLC7A5CYP1A2HSD17B10PTGS1PKM
SCHEMBL4208145 0.81 CYP1A2 (0.47) SLC7A5CYP1A2HSD17B10PTGS1PKM
SCHEMBL8168327 0.81 ESR1 (0.49) SLC7A5ESR1ESR2ALDH1A1KIF11
Hydrochloric Acid SCHEMBL25217806 0.80 CYP1A2 (0.46) SLC7A5CYP1A2HSD17B10PTGS1PKM
SCHEMBL31369948 0.80 NNMT (0.47) SLC7A5CYP1A2HSD17B10PTGS1PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1432 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-04-30 US claimed
US-20260060962-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE CAPACITY BIO INC (US) 2026-03-05 US claimed
US-12522572-B2 Isoxazole hydroxamic acids as histone deacetylase 6 inhibitors THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2026-01-13 US claimed
US-20240343697-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS THE GEORGE WASHINGTON UNIVERSITY, A CONGRESSIONALLY CHARTERED NOT-FOR-PROFIT CORPORATION (US) 2024-10-17 US claimed
EP-4284779-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE Capacity Bio, Inc. (US) 2023-12-06 EP claimed
CN-117120417-A Methods and agents for stimulating mitochondrial turnover to treat diseases 容量生物公司 2023-11-24 CN claimed
WO-2022165189-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE Capacity Bio, Inc. (US) 2022-08-04 WO claimed
US-20220233507-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE Capacity Bio, Inc. 2022-07-28 US claimed
US-11345956-B2 Methods and compositions related to prostate cancer therapeutics THE JOHNS HOPKINS UNIVERSITY (US) 2022-05-31 US claimed
EP-0313094-B1 ANTICANCER AGENT AND REAGENT FOR OBTAINING REVERTANTS MEIJI SEIKA KAISHA LTD. (JP) 1993-09-01 EP claimed
EP-0313094-A2 Anticancer agent and reagent for obtaining revertants MEIJI SEIKA KAISHA LTD. (JP) 1989-04-26 EP claimed
JP-1110627-A None JP disclosed
US-20260146082-A1 BISPECIFIC ANTI-MYOSTATIN AND ACTIVIN A ANTIBODY OR ANTIGEN BINDING FRAGMENTS THEREOF IBIO, INC. (US) 2026-05-28 US disclosed
EP-3704090-B1 MODULATORS OF THE INTEGRATED STRESS PATHWAY CALICO LIFE SCIENCES LLC (US) 2026-05-27 EP disclosed
EP-4748449-A2 USE OF SHORT CHAIN FATTY ACIDS IN CANCER PREVENTION Temple University Of The Commonwealth System Of Higher Education (US) 2026-05-27 EP disclosed
EP-0313094-B1 ANTICANCER AGENT AND REAGENT FOR OBTAINING REVERTANTS MEIJI SEIKA KAISHA LTD. (JP) 1993-09-01 EP disclosed
EP-0529655-A1 2-Piperidinecarboxylic acid derivative, oncogene suppressor and agent for obtaining revertants MEIJI SEIKA KAISHA LTD. (JP) 1993-03-03 EP disclosed
JP-H01110627-A CARCINOSTATIC AND BACK MUTANT CELL COLLECTOR MEIJI SEIKA KAISHA LTD 1989-04-27 JP disclosed
EP-0313094-A2 Anticancer agent and reagent for obtaining revertants MEIJI SEIKA KAISHA LTD. (JP) 1989-04-26 EP disclosed
EP-0313094-A2 Anticancer agent and reagent for obtaining revertants MEIJI SEIKA KAISHA LTD. (JP) 1989-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260116861-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS HDAC3, HDAC1, HDAC4 SLC7A5 1802/4885ESR1 3621/4885ESR2 2553/4885
US-20220233507-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE NLN, MAVS, PINK1 SLC7A5 2476/4885ESR1 2304/4885ESR2 1598/4885
US-20260060962-A1 METHODS AND AGENTS THAT STIMULATE MITOCHONDRIAL TURNOVER FOR TREATING DISEASE MDH2, NLN, PINK1 SLC7A5 1047/4885ESR1 3984/4885ESR2 1854/4885
US-20260146082-A1 BISPECIFIC ANTI-MYOSTATIN AND ACTIVIN A ANTIBODY OR ANTIGEN BINDING FRAGMENTS THEREOF MSTN, MST1R, MYOF SLC7A5 4441/4885ESR1 1873/4885ESR2 1807/4885
US-20240343697-A1 ISOXAZOLE HYDROXAMIC ACIDS AS HISTONE DEACETYLASE 6 INHIBITORS HDAC1, HDAC7, HDAC5 SLC7A5 3138/4885ESR1 2719/4885ESR2 3368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.