Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 5/20 | 0.37 |
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | DPP4 | P27487 | 3/20 | 0.36 |
| ▸ | ALPL | P05186 | 2/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5291917 | 0.84 | CNR1 (0.37) | CRHR1CNR1DPP4ALPLMRGPRX4 | |
| SCHEMBL4017079 | 0.83 | CRHR1 (0.35) | CRHR1MRGPRX4KDM4E | |
| SCHEMBL3536164 | 0.83 | DPP4 (0.43) | CNR1DPP4ALPLMRGPRX4KDM4E | |
| SCHEMBL5775424 | 0.74 | EGLN2 (0.41) | MRGPRX4 | |
| SCHEMBL5290255 | 0.72 | CRHR1 (0.38) | CRHR1CNR1DPP4ALPLSHMT2 | |
| SCHEMBL4505734 | 0.71 | EGLN2 (0.40) | DPP4MRGPRX4KDM4EMAPTNPC1 | |
| SCHEMBL5771739 | 0.69 | EGLN2 (0.37) | MRGPRX4 | |
| SCHEMBL5768799 | 0.69 | EGLN2 (0.37) | MRGPRX4 | |
| SCHEMBL3258832 | 0.69 | CRHR1 (0.35) | CRHR1MRGPRX4KDM4EMAPTNPC1 | |
| SCHEMBL5771022 | 0.69 | MEN1 (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1853607-A2 | PYRAZOLOPYRIMIDINES | Bayer CropScience AG (DE) | 2007-11-14 | — | — | EP | disclosed |
| WO-2006087120-A2 | PYRAZOLOPYRIMIDINES | BAYER CROPSCIENCE AG (DE) | 2006-08-24 | — | — | WO | disclosed |