Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 3/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3258832 | 0.84 | CRHR1 (0.35) | CRHR1TYK2MRGPRX4ALDH1A1KDM4E | |
| SCHEMBL5283300 | 0.83 | CRHR1 (0.37) | CRHR1MRGPRX4KDM4E | |
| SCHEMBL2796946 | 0.83 | ALDH1A1 (0.42) | CRHR1TYK2MRGPRX4ALDH1A1KDM4E | |
| SCHEMBL4019201 | 0.80 | CRHR1 (0.33) | CRHR1TYK2 | |
| SCHEMBL5324293 | 0.74 | KDM4E (0.43) | CRHR1ALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3260212 | 0.72 | CRHR1 (0.33) | CRHR1TYK2 | |
| SCHEMBL5291917 | 0.69 | CNR1 (0.37) | CRHR1MRGPRX4 | |
| SCHEMBL5771022 | 0.69 | MEN1 (0.33) | ALDH1A1 | |
| SCHEMBL3265665 | 0.69 | PDE4A (0.31) | — | |
| SCHEMBL5774361 | 0.68 | CDK4 (0.32) | ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014661-A1 | Hererocyclically substituted heterocyclic carboxylic acid derivates | Bayer CropScience AG (DE) | 2009-01-14 | — | — | EP | disclosed |