Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL240824 | 0.89 | ALDH1A1 (0.33) | ALDH1A1NPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL238449 | 0.83 | HTR2C (0.41) | ALDH1A1NPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL4986665 | 0.82 | GABRA1 (0.40) | ALDH1A1NPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL13993580 | 0.82 | ALDH1A1 (0.39) | ALDH1A1NPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL239478 | 0.82 | KMT2A (0.43) | ALDH1A1NPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL240763 | 0.82 | KMT2A (0.42) | ALDH1A1NPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL242365 | 0.81 | HTR1A (0.38) | — | |
| SCHEMBL243661 | 0.80 | EHMT2 (0.42) | TDP1 | |
| SCHEMBL242600 | 0.77 | ALDH1A1 (0.36) | ALDH1A1NPSR1LMNAHTTSMN1; SMN2 | |
| SCHEMBL238448 | 0.77 | ALDH1A1 (0.37) | ALDH1A1NPSR1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012015901-A1 | METHODS FOR TREATING GASTRIC AND PANCREATIC MALIGNANCIES | GENZYME CORPORATION (US) | 2012-02-02 | — | — | WO | disclosed |