Potassium

Potassium

SCHEMBL5283548

O=S(=O)(Oc1cccc(F)c1F)c1cc(F)c(F)cc1F.[K]

nearest known ligand 0.37

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.37
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
PTGES2 Q9H7Z7 2/20 0.34
AKR1B1 P15121 1/20 0.33
SLC22A12 Q96S37 1/20 0.33
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
GAA P10253 2/20 0.33
ESR1 P03372 1/20 0.33
ESR2 Q92731 1/20 0.33
MAPK1 P28482 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
SENP8 Q96LD8 1/20 0.32
SENP7 Q9BQF6 1/20 0.32
SENP6 Q9GZR1 1/20 0.32
ELANE P08246 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778130 0.75 SLC6A2 (0.43) HTR6SLC6A2SLC6A4SLC6A3PTGES2
SCHEMBL4121037 0.75 ALDH1A1 (0.53) HTR6SLC6A2SLC6A4SLC6A3KMT2A
SCHEMBL26664896 0.73 ELANE (0.52) HTR6SLC6A2SLC6A4SLC6A3PTGES2
SCHEMBL18632038 0.72 CES2 (0.41) SLC6A2SLC6A4SLC6A3SLC22A12KMT2A
SCHEMBL3744673 0.72 SLC6A2 (0.41) HTR6SLC6A2SLC6A4SLC6A3SLC22A12
SCHEMBL4138938 0.71 KMT2A (0.56) HTR6KMT2AMEN1GAAESR1
SCHEMBL1617240 0.71 HTR6 (0.34) HTR6KMT2AMEN1GAAESR1
SCHEMBL15763976 0.70 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3PTGES2AKR1B1
SCHEMBL30490527 0.70 SLC6A2 (0.40) SLC6A2SLC6A4SLC6A3PTGES2AKR1B1
SCHEMBL30919460 0.69 SLC6A2 (0.39) SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1458799-B1 TRANSLUCENT FLAME RETARDANT POLYCARBONATE COMPOSITIONS GEN ELECTRIC (US) 2007-11-28 EP disclosed
EP-1458799-A1 TRANSLUCENT FLAME RETARDANT POLYCARBONATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2004-09-22 EP disclosed
WO-2003050176-A1 TRANSLUCENT FLAME RETARDANT POLYCARBONATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2003-06-19 WO disclosed
US-6462111-B1 ENCAPSULATED POLYTETRAFLUOROETHYLENE, BROMINE AND CHLORINE FREE FIRE RETARDANT AND OPTIONALLY A SILOXANE, SUCH AS OCTAPHENYLCYCLOTETRASILOXANE; LOW HAZE AND HIGH TRANSPARENCY; INJECTION MOLDING AND/OR THIN WALL APPLICATIONS GENERAL ELECTRIC COMPANY 2002-10-08 US disclosed