SCHEMBL528359

SCHEMBL528359

C=C(CC(=O)OCc1ccccc1)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
MAPK1 P28482 1/20 0.59
L3MBTL1 Q9Y468 1/20 0.59
LMNA P02545 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
SLC6A2 P23975 1/20 0.50
SLC6A3 Q01959 1/20 0.50
KMT2A Q03164 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
NPC1 O15118 1/20 0.47
RAB9A P51151 1/20 0.47
HCAR2 Q8TDS4 1/20 0.46
CDC25B P30305 1/20 0.45
CA12 O43570 1/20 0.45
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
CA9 Q16790 1/20 0.45
POLB P06746 1/20 0.44
HTT P42858 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10873748 0.98 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1LMNATDP1
SCHEMBL1045139 0.88 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1LMNATDP1
SCHEMBL11989305 0.86 ALDH1A1 (0.43) ALDH1A1MAPK1L3MBTL1LMNATDP1
SCHEMBL27494446 0.85 ALDH1A1 (0.63) ALDH1A1MAPK1L3MBTL1LMNATDP1
SCHEMBL22616084 0.85 KMT2A (0.46) ALDH1A1MAPK1L3MBTL1LMNAKMT2A
SCHEMBL294341 0.85 ALDH1A1 (0.73) ALDH1A1MAPK1L3MBTL1LMNATDP1
SCHEMBL31634981 0.84 ALDH1A1 (0.58) ALDH1A1MAPK1L3MBTL1LMNATDP1
SCHEMBL28742954 0.83 ALDH1A1 (0.53) ALDH1A1MAPK1L3MBTL1LMNATDP1
SCHEMBL7974068 0.83 TDP1 (0.56) ALDH1A1MAPK1L3MBTL1LMNATDP1
SCHEMBL8069055 0.83 ALDH1A1 (0.70) ALDH1A1MAPK1L3MBTL1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 484 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798080-A Preparation method of (R) -5- ([ 1,1' -biphenyl ] -4-yl) -2-methyl-4-oxopentanoic acid calcium salt 杭州科巢生物科技有限公司 2025-04-11 CN claimed
CN-113462443-B Diesel antiwear agent composition, preparation method thereof and diesel oil composition 中国石油化工股份有限公司 2023-07-14 CN claimed
US-20230151290-A1 LUBRICITY MODIFIER FOR FUELS AND APPLICATION THEREOF CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2023-05-18 US claimed
EP-4130206-A1 FUEL LUBRICITY IMPROVER AND APPLICATION THEREOF China Petroleum & Chemical Corporation (CN) 2023-02-08 EP claimed
CN-111925735-B Directional heat dissipation composite adhesive film and preparation method thereof 南京工程学院 2022-06-10 CN claimed
CN-113462443-A Diesel antiwear agent composition, preparation method thereof and diesel composition 中国石油化工股份有限公司 2021-10-01 CN claimed
CN-111925735-A Directional heat dissipation composite adhesive film and preparation method thereof 南京工程学院 2020-11-13 CN claimed
EP-2145921-B1 Vulcanizable polymer compositions ARLANXEO DEUTSCHLAND GMBH (DE) 2017-01-25 EP claimed
US-8952099-B2 Vulcanizable polymer compositions LANXESS DEUTSCHLAND GMBH (DE) 2015-02-10 US claimed
EP-2199326-B1 Vulcanizable polymer compositions LANXESS DEUTSCHLAND GMBH (DE) 2014-10-29 EP claimed
US-8283413-B2 ink-jet ink; improved stability and dispersibility; polymerized hydrophobic acid-functionalized monomer includes 2-(benzyloxycarbonylmethyl)acrylic acid HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2012-10-09 US claimed
US-20100179277-A1 VULCANIZABLE POLYMER COMPOSITIONS LANXESS DEUTSCHLAND GMBH (DE) 2010-07-15 US claimed
EP-2199326-A1 Vulcanizable polymer compositions Lanxess Deutschland GmbH (DE) 2010-06-23 EP claimed
US-20100029857-A1 VULCANIZABLE POLYMER COMPOSITIONS LANXESS DEUTSCHLAND GMBH (DE) 2010-02-04 US claimed
EP-2145920-A1 Vulcanizable polymer compositions Lanxess Deutschland GmbH (DE) 2010-01-20 EP claimed
EP-2145921-A1 Vulcanizable polymer compositions Lanxess Deutschland GmbH (DE) 2010-01-20 EP claimed
US-20080182934-A1 Acid-functionalized hydrophobic monomer emulsions, latexes, and associated latexes HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2008-07-31 US claimed
EP-4368686-B1 LUBRICITY IMPROVER COMPOSITION FOR FUEL OIL AND USE THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2026-05-27 EP disclosed
EP-0108985-A1 Transparent resin material containing metal atoms HITACHI, LTD. (JP) 1984-05-23 EP disclosed
US-4341781-A HYPOTENSIVE AGENTS HOFFMANN-LA ROCHE INC. (US) 1982-07-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230151290-A1 LUBRICITY MODIFIER FOR FUELS AND APPLICATION THEREOF F12, ACADM, ADH1A ALDH1A1 69/4885MAPK1 2591/4885L3MBTL1 3371/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.