Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 8/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 6/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11903187 | 0.85 | LMNA (0.56) | NOTUMRAB9ASMN1; SMN2TDP1NPC1 | |
| SCHEMBL12002394 | 0.83 | NOTUM (0.58) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL6964641 | 0.83 | NOTUM (0.58) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL14210011 | 0.81 | NOTUM (0.65) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL27163685 | 0.81 | NOTUM (0.55) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1544128 | 0.80 | NOTUM (1.00) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL31686265 | 0.78 | NOTUM (0.59) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL5282505 | 0.77 | NOTUM (0.51) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL4050311 | 0.77 | NOTUM (0.74) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL23881773 | 0.77 | NOTUM (0.63) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107501200-B | Organic small molecule with recognition effect on ammonia water, methylamine and aniline and recognition method thereof | 河南工程学院 | 2020-05-15 | — | — | CN | disclosed |
| CN-107501200-B | Organic small molecule with recognition effect on ammonia water, methylamine and aniline and recognition method thereof | 河南工程学院 | 2020-05-15 | — | — | CN | disclosed |
| CN-107501200-A | Organic small molecule with recognition effect on ammonia water, methylamine and aniline and recognition method thereof | 河南工程学院 | 2017-12-22 | — | — | CN | disclosed |
| CN-101723941-A | “1,2,4” oxadiazole as a metabotropic glutamate receptor-5 modulator | ASTRAZENECA AB | 2010-06-09 | — | — | CN | disclosed |
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | NOTUM 3506/4885RAB9A 20/4885SMN1; SMN2 3894/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.