Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 8/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12002394 | 0.85 | NOTUM (0.58) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL27163685 | 0.83 | NOTUM (0.55) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL5283705 | 0.83 | NOTUM (0.67) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL5282505 | 0.80 | NOTUM (0.51) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL14210011 | 0.75 | NOTUM (0.65) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL6970965 | 0.75 | ALDH1A1 (0.67) | RAB9ASMN1; SMN2ALDH1A1NPC1KMT2A | |
| SCHEMBL1544128 | 0.74 | NOTUM (1.00) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL28225146 | 0.74 | NOTUM (0.68) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL6965688 | 0.73 | EPHX2 (0.40) | RAB9ASMN1; SMN2ALDH1A1CYP2C19NPC1 | |
| SCHEMBL1233832 | 0.73 | NOTUM (0.66) | NOTUMRAB9ASMN1; SMN2ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1329160-A2 | 4-ACYLAMINOPYRAZOLE DERIVATIVES | Sankyo Company, Limited (JP) | 2003-07-23 | — | — | EP | disclosed |