Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 13/20 | 0.55 |
| ▸ | GABRB2 | P47870 | 13/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.55 |
| ▸ | CNR2 | P34972 | 5/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.48 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.48 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.48 |
| ▸ | RXRA | P19793 | 1/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.48 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL726993 | 0.93 | GABRA1 (0.53) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL725656 | 0.90 | GABRA1 (0.50) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL526389 | 0.90 | GABRA1 (0.54) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL525793 | 0.88 | GABRA1 (0.54) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL525883 | 0.84 | GABRA1 (0.59) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL10077358 | 0.84 | GABRA1 (0.49) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL526406 | 0.83 | GABRA1 (0.58) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL724631 | 0.81 | GABRA1 (0.49) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL725503 | 0.79 | GABRA1 (0.49) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL526354 | 0.77 | GABRA1 (0.57) | GABRA1GABRB2ALOX5CNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012013691-A1 | MULTITARGET SUBSTITUTED BIPHENYL DIOL DERIVATIVES | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |