Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 14/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 14/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 8/20 | 0.50 |
| ▸ | CNR2 | P34972 | 5/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.44 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.44 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10077358 | 0.94 | GABRA1 (0.49) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL724631 | 0.91 | GABRA1 (0.49) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL528431 | 0.90 | GABRA1 (0.55) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL725503 | 0.89 | GABRA1 (0.49) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL726993 | 0.84 | GABRA1 (0.53) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL526389 | 0.81 | GABRA1 (0.54) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL525883 | 0.80 | GABRA1 (0.59) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| Hydrochloric Acid SCHEMBL526406 | 0.79 | GABRA1 (0.58) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL525793 | 0.79 | GABRA1 (0.54) | GABRA1GABRB2ALOX5CNR2CNR1 | |
| SCHEMBL21102963 | 0.75 | SLC6A9 (0.43) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423181-A1 | Multitarget substituted biphenyl diol derivatives | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH S.A. (ES) | 2012-02-29 | — | — | EP | disclosed |
| EP-2423181-A1 | Multitarget substituted biphenyl diol derivatives | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH S.A. (ES) | 2012-02-29 | — | — | EP | disclosed |
| WO-2012013691-A1 | MULTITARGET SUBSTITUTED BIPHENYL DIOL DERIVATIVES | PROUS INSTITUTE FOR BIOMEDICAL RESEARCH, S.A. (ES) | 2012-02-02 | — | — | WO | disclosed |