Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 4/20 | 0.50 |
| ▸ | DBF4 | Q9UBU7 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | AKT2 | P31751 | 2/20 | 0.39 |
| ▸ | PRKACA | P17612 | 1/20 | 0.39 |
| ▸ | PRKACG | P22612 | 1/20 | 0.39 |
| ▸ | PRKACB | P22694 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.37 |
| ▸ | CDK1 | P06493 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MGMT | P16455 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4496030 | 0.90 | CDC7 (0.60) | CDC7DBF4LMNASLC7A5PDPK1 | |
| Tyrosine SCHEMBL9732191 | 0.78 | SLC7A5 (0.56) | CDC7DBF4LMNASLC7A5AKT2 | |
| Tyrosine SCHEMBL528458 | 0.75 | SLC7A5 (0.61) | SLC7A5KDM4E | |
| Tyrosine SCHEMBL528455 | 0.75 | SLC7A5 (0.61) | SLC7A5KDM4E | |
| SCHEMBL669596 | 0.73 | CDC7 (0.39) | CDC7DBF4LMNAPDPK1AKT2 | |
| SCHEMBL4397297 | 0.72 | PDPK1 (0.55) | CDC7DBF4LMNAPDPK1PRKACA | |
| SCHEMBL2938609 | 0.72 | PDPK1 (0.62) | CDC7DBF4LMNAPDPK1PRKACA | |
| SCHEMBL27680265 | 0.71 | SLC7A5 (0.67) | SLC7A5 | |
| SCHEMBL4453960 | 0.71 | SLC7A5 (0.67) | SLC7A5 | |
| SCHEMBL8187698 | 0.71 | PDPK1 (0.53) | CDC7DBF4LMNAPDPK1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598873-A2 | BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME | Metabolon, Inc. (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012015904-A2 | BIOMARKERS FOR PROSTATE CANCER AND METHODS USING THE SAME | METABOLON, INC. (US) | 2012-02-02 | — | — | WO | disclosed |
| US-4212944-A | AEROBICALLY PROPAGATING NOCARDIOPSIS ATRA | PFIZER INC. (US) | 1980-07-15 | — | — | US | disclosed |