Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHKA | P35790 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 1/20 | 0.38 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL251401 | 0.82 | TDP1 (0.47) | SMN1; SMN2ALDH1A1TP53TDP1NAMPT | |
| Trimethylammonium SCHEMBL6671555 | 0.81 | MYC (0.48) | MAPTSMN1; SMN2ALDH1A1TP53TDP1 | |
| SCHEMBL10965132 | 0.81 | ALDH1A1 (0.43) | MAPTALDH1A1TP53TDP1NAMPT | |
| SCHEMBL8778699 | 0.81 | CHRM5 (0.46) | CHRM5CHKAMAPTALDH1A1TDP1 | |
| SCHEMBL8429962 | 0.81 | CHRM5 (0.46) | CHRM5CHKAMAPTSMN1; SMN2ALDH1A1 | |
| Pyridine SCHEMBL28150876 | 0.80 | TDP1 (0.46) | SMN1; SMN2ALDH1A1TP53TDP1NAMPT | |
| SCHEMBL1748 | 0.79 | MYC (0.53) | SMN1; SMN2ALDH1A1TP53TDP1MYC | |
| SCHEMBL29392580 | 0.79 | MYC (0.53) | SMN1; SMN2ALDH1A1TP53TDP1MYC | |
| Toluene SCHEMBL2454660 | 0.79 | CHRM5 (0.55) | CHRM5CHKAMAPTSMN1; SMN2ALDH1A1 | |
| Pyridine SCHEMBL28284596 | 0.79 | TDP1 (0.49) | SMN1; SMN2ALDH1A1TP53TDP1NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10023689-B2 | Functional biodegradable polymers | THE UNIVERSITY OF AKRON | 2018-07-17 | — | — | US | claimed |
| US-20160229952-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | NATIONAL SCIENCE FOUNDATION | 2016-08-11 | — | — | US | claimed |
| US-20130184429-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | THE UNIVERSITY OF AKRON (US) | 2013-07-18 | — | — | US | claimed |
| US-20100010194-A1 | Method for Preparing a Polymer Conjugate | NEKTAR THERAPEUTICS AL, CORPORATION | 2010-01-14 | — | — | US | claimed |
| US-10023689-B2 | Functional biodegradable polymers | THE UNIVERSITY OF AKRON | 2018-07-17 | — | — | US | disclosed |
| US-20160229952-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | NATIONAL SCIENCE FOUNDATION | 2016-08-11 | — | — | US | disclosed |
| US-20130184429-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | THE UNIVERSITY OF AKRON (US) | 2013-07-18 | — | — | US | disclosed |
| EP-2598552-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | University Of Akron (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012015481-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | UNIVERSITY OF AKRON (US) | 2012-02-02 | — | — | WO | disclosed |
| WO-2007087256-A2 | METHOD OF PREPARING DENDRITIC DRUGS | CENTRAL MICHIGAN UNIVERSITY BOARD OF TRUSTEES (US) | 2007-08-02 | — | — | WO | disclosed |
| EP-1734936-A2 | AMPHIPHILIC STAR-LIKE OR SCOPRION-LIKE MACROMOLECULES, VARIOUS COMPOSITIONS AND USES THEREOF | Rutgers, The State University (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005074887-A2 | AMPHIPHILIC STAR-LIKE OR SCORPION-LIKE MACROMOLECULES, VARIOUS COMPOSITIONS AND USES THEREOF | RUTGERS, THE STATE UNIVERSITY (US) | 2005-08-18 | — | — | WO | disclosed |
| WO-2002054141-A2 | DISCOTIC LIQUID CRYSTAL MATERIALS AND O-PLATE COMPENSATION FILMS MADE THEREFROM | THE UNIVERSITY OF AKRON (US) | 2002-07-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100010194-A1 | Method for Preparing a Polymer Conjugate | ALG1, PHOSPHO1, DDOST | CHRM5 2111/4885CHKA 954/4885MAPT 822/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.