Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CHKA | P35790 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyridine SCHEMBL126094 | 0.82 | ESR2 (0.49) | POLBRECQLESR2L3MBTL1HPGD | |
| SCHEMBL121153 | 0.81 | LMNA (0.53) | POLBRECQLESR2L3MBTL1HPGD | |
| SCHEMBL528465 | 0.81 | CHRM5 (0.50) | CHRM5CHKAL3MBTL1ALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL1924833 | 0.79 | LMNA (0.51) | POLBRECQLESR2L3MBTL1HPGD | |
| Hydrochloric Acid SCHEMBL5858440 | 0.79 | LMNA (0.51) | POLBRECQLESR2L3MBTL1HPGD | |
| Water SCHEMBL3002925 | 0.79 | LMNA (0.51) | POLBRECQLESR2L3MBTL1HPGD | |
| Acetic Acid SCHEMBL1232489 | 0.75 | LMNA (0.47) | POLBRECQLESR2HPGDLMNA | |
| Ethylene Glycol SCHEMBL6331832 | 0.75 | LMNA (0.51) | POLBRECQLESR2HPGDLMNA | |
| SCHEMBL3369695 | 0.74 | LMNA (0.51) | POLBRECQLESR2L3MBTL1HPGD | |
| Isopropylamine SCHEMBL2350745 | 0.73 | LMNA (0.46) | POLBRECQLESR2HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656026-B1 | POLYARYLATES CONTAINING DERIVATIVES OF THE NATURAL AMINO ACID L-TYROSINE | UNIV RUTGERS (US) | 1999-11-17 | — | — | EP | claimed |