SCHEMBL5284832

SCHEMBL5284832

CCCn1nnc(Cl)c1[N+](=O)[O-]

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.34
CYP1A2 P05177 3/20 0.34
SLC9A1 P19634 1/20 0.34
RAB9A P51151 1/20 0.33
TOP2A P11388 1/20 0.33
KDM4E B2RXH2 1/20 0.32
CYP2C19 P33261 2/20 0.31
MEN1 O00255 3/20 0.31
KMT2A Q03164 3/20 0.31
GRIA4 P48058 1/20 0.31
HCAR3 P49019 1/20 0.31
CYP2C9 P11712 1/20 0.31
GRM2 Q14416 1/20 0.31
GAA P10253 2/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
LMNA P02545 2/20 0.31
MAPT P10636 2/20 0.31
HTT P42858 2/20 0.31
NPSR1 Q6W5P4 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5274598 0.90 SLC9A1 (0.37) ALDH1A1CYP1A2SLC9A1TOP2AKDM4E
SCHEMBL5277272 0.87 SLC9A1 (0.40) ALDH1A1SLC9A1TOP2AHCAR3LMNA
SCHEMBL5282121 0.86 NPC1 (0.33) ALDH1A1CYP1A2SLC9A1KDM4ECYP2C19
SCHEMBL5285281 0.81 ALDH1A1 (0.36) ALDH1A1CYP1A2SLC9A1TOP2AKDM4E
SCHEMBL5279828 0.81 SLC9A1 (0.35) ALDH1A1CYP1A2SLC9A1TOP2AGRIA4
SCHEMBL5283087 0.81 GRM2 (0.38) ALDH1A1SLC9A1TOP2AGRIA4HCAR3
SCHEMBL5279426 0.79 TOP2A (0.36) ALDH1A1SLC9A1TOP2AMEN1KMT2A
SCHEMBL5284112 0.79 SLC9A1 (0.34) ALDH1A1SLC9A1TOP2AGRIA4HCAR3
SCHEMBL5280161 0.79 ALDH1A1 (0.32) ALDH1A1SLC9A1TOP2A
SCHEMBL5275930 0.78 SMN1; SMN2 (0.39) ALDH1A1SLC9A1TOP2AGRIA4HCAR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed