SCHEMBL5280161

SCHEMBL5280161

CCCn1nnc(C(Cl)(Cl)Cl)c1[N+](=O)[O-]

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
SLC9A1 P19634 1/20 0.32
TOP2A P11388 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5280352 0.91 SLC9A1 (0.35) ALDH1A1SLC9A1TOP2A
SCHEMBL5274192 0.88 SLC9A1 (0.38) ALDH1A1SLC9A1
SCHEMBL5280698 0.88 ALDH1A1 (0.31) ALDH1A1SLC9A1
SCHEMBL5279157 0.87 NPC1 (0.31)
SCHEMBL5280475 0.86 MAPT (0.36) ALDH1A1SLC9A1TOP2A
SCHEMBL5279750 0.84 ALDH1A1 (0.37) ALDH1A1SLC9A1TOP2A
SCHEMBL5278570 0.82 ALDH1A1 (0.31) ALDH1A1SLC9A1
SCHEMBL5279959 0.80 SLC9A1 (0.33) SLC9A1TOP2A
SCHEMBL5284832 0.79 ALDH1A1 (0.34) ALDH1A1SLC9A1TOP2A
SCHEMBL5280420 0.78 PKM (0.33) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1859781-A2 Brightening and/or colouring agent with triazoles Henkel Kommanditgesellschaft auf Aktien (DE) 2007-11-28 EP disclosed