Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CDC25B | P30305 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5282389 | 0.79 | ALDH1A1 (0.53) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL5282555 | 0.70 | LMNA (0.49) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL26696627 | 0.69 | ALDH1A1 (0.56) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL217571 | 0.69 | ALDH1A1 (0.77) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL5284001 | 0.68 | ALDH1A1 (0.44) | ALDH1A1MAPK1L3MBTL1MAPTHSD17B10 | |
| Bicarbonate SCHEMBL23001581 | 0.67 | ALDH1A1 (0.74) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL29901825 | 0.67 | ALDH1A1 (0.74) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL294341 | 0.67 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL1177836 | 0.67 | ALDH1A1 (0.73) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 | |
| SCHEMBL8681578 | 0.66 | ALDH1A1 (0.61) | ALDH1A1MAPK1L3MBTL1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |