Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | FAAH | O00519 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.51 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.51 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.51 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.51 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.51 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.51 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.50 |
| ▸ | TNKS | O95271 | 1/20 | 0.50 |
| ▸ | PARP1 | P09874 | 1/20 | 0.50 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27689302 | 0.90 | PARP14 (0.52) | PARP14 | |
| SCHEMBL5284883 | 0.85 | FAAH (0.62) | FAAHPOLBMAPTNPSR1GRIN2D | |
| SCHEMBL5180419 | 0.85 | POLB (0.63) | GAAFAAHPOLBMAPTNPSR1 | |
| SCHEMBL28766049 | 0.83 | PARP14 (0.57) | GAAFAAHPOLBMAPTNPSR1 | |
| SCHEMBL4247873 | 0.82 | GAA (0.58) | GAAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL13234936 | 0.80 | FAAH (0.82) | FAAHPOLBMAPTNPSR1GRIN2D | |
| SCHEMBL4239619 | 0.80 | GAA (0.65) | GAAFAAHGRIN2DGRIN3BGRIN1 | |
| SCHEMBL5165728 | 0.80 | GAA (0.65) | GAAFAAHKMT2AMEN1 | |
| SCHEMBL4768629 | 0.80 | GAA (0.67) | GAAPOLBMAPTNPSR1KMT2A | |
| SCHEMBL4244729 | 0.79 | GAA (0.56) | GAAFAAHPOLBMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |