Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 4/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5169749 | 0.93 | FAAH (0.67) | FAAHKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL5180412 | 0.87 | FAAH (0.65) | FAAHKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL13234936 | 0.86 | FAAH (0.82) | FAAHKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL5284886 | 0.85 | GAA (0.56) | FAAHKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL5165692 | 0.84 | ADAMTS5 (0.60) | FAAHKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL4247871 | 0.83 | KMT2A (0.62) | FAAHKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL4239616 | 0.83 | FAAH (0.61) | FAAHKMT2AMEN1POLBGRIN2D | |
| SCHEMBL5165726 | 0.82 | FAAH (0.60) | FAAHKMT2AMEN1POLB | |
| SCHEMBL4244727 | 0.81 | FAAH (0.56) | FAAHKMT2ASMN1; SMN2MEN1POLB | |
| SCHEMBL5170570 | 0.78 | HTT (0.73) | FAAHKMT2ASMN1; SMN2MEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1771429-A1 | NEW BENZOYL UREA DERIVATIVES | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2007-04-11 | — | — | EP | disclosed |
| WO-2006010966-A1 | NEW BENZOYL UREA DERIVATIVES | Richter Gedeon Vegyészeti Gyár Rt. (HU) | 2006-02-02 | — | — | WO | disclosed |