Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528269 | 0.91 | NPSR1 (0.53) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL529288 | 0.90 | MAPT (0.58) | MAPTHTTGAAKDM4EHPGD | |
| SCHEMBL528500 | 0.88 | MAPT (0.77) | MAPTHTTGAAKDM4EHPGD | |
| SCHEMBL529256 | 0.87 | MAPT (0.66) | MAPTHTTGAAKDM4EHPGD | |
| SCHEMBL528300 | 0.85 | MAPT (0.63) | MAPTHTTGAAKDM4EHPGD | |
| SCHEMBL528294 | 0.84 | KDM4E (0.65) | MAPTHTTGAAKDM4EHPGD | |
| SCHEMBL529461 | 0.83 | MAPT (0.50) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL528351 | 0.82 | MAPT (0.48) | MAPTHTTKDM4EHPGDLMNA | |
| SCHEMBL529361 | 0.82 | ALDH1A1 (0.50) | MAPTHTTGAAKDM4EHPGD | |
| SCHEMBL528675 | 0.81 | MAPT (0.51) | MAPTHTTKDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |