Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.65 |
| ▸ | MAPT | P10636 | 6/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 3/20 | 0.60 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529586 | 0.92 | MAPT (0.59) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL528500 | 0.90 | MAPT (0.77) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL529419 | 0.89 | MAPT (0.61) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL528449 | 0.89 | ALDH1A1 (0.67) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL528222 | 0.88 | MAPT (0.66) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL528269 | 0.87 | NPSR1 (0.53) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL529360 | 0.85 | LMNA (0.67) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL528092 | 0.85 | MAPT (0.70) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL529111 | 0.84 | MAPT (0.64) | NPSR1MAPTHTTALDH1A1KDM4E | |
| SCHEMBL528208 | 0.84 | ALDH1A1 (0.64) | NPSR1MAPTHTTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |