Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | TOP2A | P11388 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528415 | 0.92 | LMNA (0.57) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL527908 | 0.90 | MAPT (0.61) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL528588 | 0.89 | NPSR1 (0.56) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL528224 | 0.87 | ALDH1A1 (0.56) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL529217 | 0.87 | MEN1 (0.52) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL529222 | 0.84 | ALDH1A1 (0.53) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL528832 | 0.84 | MAPT (0.53) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL528469 | 0.83 | ALDH1A1 (0.57) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL528045 | 0.83 | MAPT (0.61) | ALDH1A1MAPTKDM4EHPGDLMNA | |
| SCHEMBL528098 | 0.82 | MAPT (0.56) | ALDH1A1MAPTKDM4EHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |