Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | PYGM | P11217 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528770 | 0.91 | MAPT (0.60) | NPSR1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL527908 | 0.90 | MAPT (0.61) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL528501 | 0.89 | ALDH1A1 (0.52) | NPSR1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL528415 | 0.88 | LMNA (0.57) | LMNAMAPTALDH1A1KDM4EHPGD | |
| SCHEMBL528224 | 0.87 | ALDH1A1 (0.56) | NPSR1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL529217 | 0.87 | MEN1 (0.52) | NPSR1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL528832 | 0.84 | MAPT (0.53) | NPSR1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL529222 | 0.84 | ALDH1A1 (0.53) | NPSR1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL528469 | 0.83 | ALDH1A1 (0.57) | NPSR1LMNAMAPTALDH1A1KDM4E | |
| SCHEMBL528625 | 0.83 | MAPT (0.54) | NPSR1LMNAMAPTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |