Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | SCN4A | P35499 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.38 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.38 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27646280 | 0.84 | CYP2A6 (0.52) | CNR2NOTUMIDO1CYP2D6 | |
| SCHEMBL3772831 | 0.78 | P2RX7 (0.47) | CNR2CNR1NOTUMIDO1P2RX7 | |
| SCHEMBL29746276 | 0.78 | ERN1 (0.34) | CNR2P2RX7BLM | |
| SCHEMBL6501884 | 0.72 | RORC (0.46) | CNR2CNR1NOTUMIDO1SCN9A | |
| SCHEMBL440943 | 0.71 | TSHR (0.52) | CNR2NOTUMIDO1P2RX7TSHR | |
| SCHEMBL6531978 | 0.70 | CNR2 (0.54) | CNR2CNR1IDO1 | |
| SCHEMBL2752439 | 0.70 | NOTUM (0.38) | CNR2CNR1NOTUMIDO1P2RX7 | |
| SCHEMBL4489711 | 0.70 | CNR2 (0.54) | CNR2CNR1CYP2D6MAOAMAPK1 | |
| SCHEMBL2753943 | 0.70 | CNR2 (0.43) | CNR2CNR1NOTUMIDO1P2RX7 | |
| SCHEMBL29489437 | 0.70 | CYP2A6 (0.68) | CNR2NOTUMIDO1P2RX7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598505-A2 | SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012013713-A2 | SUBSTITUTED IMIDAZO[1,2-B]PYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-02-02 | — | — | WO | disclosed |