Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.51 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11310907 | 0.90 | ALDH1A1 (0.46) | ALDH1A1HPGDKDM4EHSD17B10CASP3 | |
| SCHEMBL11316655 | 0.89 | ALDH1A1 (0.45) | ALDH1A1HPGDKDM4EHSD17B10CASP3 | |
| SCHEMBL11291980 | 0.86 | NPC1 (0.57) | ALDH1A1HPGDKDM4EHSD17B10CASP3 | |
| SCHEMBL11320415 | 0.86 | NPC1 (0.53) | ALDH1A1KDM4EHSD17B10CASP3NPC1 | |
| SCHEMBL14817806 | 0.86 | ALDH1A1 (0.65) | ALDH1A1HPGDKDM4EHSD17B10NPC1 | |
| SCHEMBL28176482 | 0.82 | HDAC3 (0.49) | ALDH1A1HPGDKDM4EHSD17B10CASP3 | |
| SCHEMBL5516360 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EHSD17B10CASP3 | |
| SCHEMBL463597 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10NPC1RAB9A | |
| SCHEMBL29904721 | 0.82 | ALDH1A1 (0.61) | ALDH1A1HPGDHSD17B10NPC1RAB9A | |
| SCHEMBL23843372 | 0.81 | CYP3A4 (0.48) | ALDH1A1KDM4EHSD17B10CASP3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117083355-A | Coating composition, kit, coating film, and method for forming coating film | 东曹株式会社 | 2023-11-17 | — | — | CN | disclosed |
| WO-2010022055-A2 | INHIBITORS OF VOLTAGE-GATED SODIUM CHANNELS | AMGEN INC. (US) | 2010-02-25 | — | — | WO | disclosed |
| WO-2007085540-A1 | 1H-INDAZ0L-4-YL-2 , 4-PYRIMIDINEDIAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007085540-A1 | 1H-INDAZ0L-4-YL-2 , 4-PYRIMIDINEDIAMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2007-08-02 | — | — | WO | disclosed |
| WO-2007028445-A1 | 6-INDOLYL-4-YL-AMINO-5-HALOGENO-2-PYRIMIDINYL-AMINO DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | WO | disclosed |
| WO-2007028445-A1 | 6-INDOLYL-4-YL-AMINO-5-HALOGENO-2-PYRIMIDINYL-AMINO DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2007-03-15 | — | — | WO | disclosed |
| US-7183415-B2 | Quinoline compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-27 | — | — | US | disclosed |
| WO-2007009681-A1 | 1 , 1-DIOXID0-2 , 3-DIHYDRO-l , 2-BENZISOTHIAZ0L-6-YL-1H-INDAZOL-4-YL-2 , 4-PYRIMIDINEDI AMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2007-01-25 | — | — | WO | disclosed |
| WO-2007009681-A1 | 1 , 1-DIOXID0-2 , 3-DIHYDRO-l , 2-BENZISOTHIAZ0L-6-YL-1H-INDAZOL-4-YL-2 , 4-PYRIMIDINEDI AMINE DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2007-01-25 | — | — | WO | disclosed |
| US-20050209213-A1 | Quinoline compound | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2005-09-22 | — | — | US | disclosed |
| US-5358949-A | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1994-10-25 | — | — | US | disclosed |
| EP-0425345-B1 | Keratinic fibres dyeing process with amino-indoles, composition and use devices | OREAL (FR) | 1994-09-14 | — | — | EP | disclosed |
| EP-0371332-B1 | Reactive dyes | BAYER AG (DE) | 1993-10-27 | — | — | EP | disclosed |
| US-5254135-A | Applying indole dye, developing with oxidizing system | L'OREAL (FR) | 1993-10-19 | — | — | US | disclosed |
| US-5070193-A | REACTIVE PHTHALOCYANINE DYESTUFFS | BAYER AAKATIENGESELLSCHAFT (DE) | 1991-12-03 | — | — | US | disclosed |
| US-5051501-A | Reactive phthalocyanine dyestuffs containing a fluorochloropyrimidinyl group | BAYER AKTIENGESELLSCHAFT (DE) | 1991-09-24 | — | — | US | disclosed |
| CN-1051669-A | With the method for amino indole dyeing keratinous fibres, compositions and facilities and equipments | OREAL (FR) | 1991-05-29 | — | — | CN | disclosed |
| EP-0425345-A1 | Keratinic fibres dyeing process with amino-indoles, composition and use devices | L'OREAL (FR) | 1991-05-02 | — | — | EP | disclosed |
| EP-0236140-A2 | Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1987-09-09 | — | — | EP | disclosed |
| EP-0056475-A2 | Pharmaceutical compositions | MERCK PATENT GmbH (DE) | 1982-07-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050209213-A1 | Quinoline compound | MC1R, MC2R, TYR | ALDH1A1 1174/4885HPGD 499/4885KDM4E 2112/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.