Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.50 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528344 | 0.91 | MAPT (0.56) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL528112 | 0.90 | KMT2A (0.70) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL529348 | 0.87 | SMN1; SMN2 (0.51) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL529523 | 0.87 | MAPT (0.56) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL528321 | 0.86 | MEN1 (0.48) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL528145 | 0.85 | MAPT (0.55) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL529227 | 0.85 | MAPT (0.57) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL528589 | 0.84 | MEN1 (0.52) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL529092 | 0.83 | KMT2A (0.59) | MEN1KMT2AMAPTNPSR1LMNA | |
| SCHEMBL529458 | 0.83 | MAPT (0.52) | MEN1KMT2AMAPTNPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |