Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL529523 | 0.91 | MAPT (0.56) | MAPTKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL528112 | 0.86 | KMT2A (0.70) | MAPTKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL528554 | 0.85 | MEN1 (0.57) | MAPTKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL529092 | 0.84 | KMT2A (0.59) | MAPTKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL528474 | 0.84 | KCNK3 (0.53) | MAPTKMT2AALDH1A1MAPK1L3MBTL1 | |
| SCHEMBL527890 | 0.82 | MAPT (0.62) | MAPTKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL528415 | 0.82 | LMNA (0.57) | MAPTKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL528835 | 0.80 | MAPT (0.62) | MAPTKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL528145 | 0.80 | MAPT (0.55) | MAPTKMT2ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL528847 | 0.80 | MEN1 (0.55) | MAPTKMT2ASMN1; SMN2LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |