Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 7/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528391 | 0.90 | MAPT (0.62) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL529092 | 0.86 | KMT2A (0.59) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL529458 | 0.86 | MAPT (0.52) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL529523 | 0.85 | MAPT (0.56) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL528554 | 0.85 | MEN1 (0.57) | MAPTMEN1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL528261 | 0.84 | MAPK1 (0.58) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL528632 | 0.83 | ALDH1A1 (0.51) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL528112 | 0.83 | KMT2A (0.70) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL528834 | 0.82 | MAPT (0.62) | MAPTHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL529422 | 0.82 | NPC1 (0.53) | MAPTHTTMEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |