Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.52 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.52 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 4/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL527890 | 0.91 | MAPT (0.62) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL529092 | 0.91 | KMT2A (0.59) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL529227 | 0.91 | MAPT (0.57) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL528835 | 0.90 | MAPT (0.62) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL528112 | 0.88 | KMT2A (0.70) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL528625 | 0.87 | MAPT (0.54) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL528554 | 0.87 | MEN1 (0.57) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL528632 | 0.86 | ALDH1A1 (0.51) | MAPTMEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL528145 | 0.85 | MAPT (0.55) | MAPTLMNAMEN1KMT2ANPSR1 | |
| SCHEMBL528261 | 0.83 | MAPK1 (0.58) | MAPTMEN1KMT2ANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |