Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.47 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | BRAF | P15056 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528757 | 0.90 | MAPT (0.54) | CCR2P2RY2GPR17SIRT2CNR1 | |
| SCHEMBL528374 | 0.90 | SMN1; SMN2 (0.45) | SIRT2ROCK2MAPTLMNAPOLB | |
| SCHEMBL528642 | 0.89 | LMNA (0.48) | CCR2P2RY2GPR17SIRT2CNR1 | |
| SCHEMBL529437 | 0.88 | MAPT (0.58) | CCR2GPR17MAPTLMNASMN1; SMN2 | |
| SCHEMBL528124 | 0.87 | KMT2A (0.53) | MAPTLMNASMN1; SMN2NPSR1 | |
| SCHEMBL527969 | 0.87 | MAPT (0.60) | P2RY2GPR17SIRT2MAPTLMNA | |
| SCHEMBL528238 | 0.86 | MAPT (0.59) | CCR2SIRT2MAPTLMNAPOLB | |
| SCHEMBL528931 | 0.86 | MAPT (0.47) | CCR2GPR17CNR1MAPTLMNA | |
| SCHEMBL529226 | 0.86 | SMN1; SMN2 (0.48) | MAPTLMNAPOLBSMN1; SMN2BRAF | |
| SCHEMBL528329 | 0.83 | MAPT (0.47) | ROCK2MAPTLMNASMN1; SMN2BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |