Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.77 |
| ▸ | LMNA | P02545 | 4/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.52 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.51 |
| ▸ | RELA | Q04206 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528901 | 0.91 | MAPT (0.74) | MAPTLMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL528794 | 0.90 | MAPT (0.62) | MAPTLMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL529003 | 0.90 | MAPT (0.66) | MAPTLMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL527890 | 0.89 | MAPT (0.62) | MAPTLMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL528683 | 0.89 | MAPT (0.77) | MAPTLMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL529579 | 0.88 | MAPT (0.61) | MAPTLMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL528499 | 0.87 | MAPT (0.63) | MAPTLMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL528590 | 0.87 | MAPT (0.63) | MAPTLMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL527969 | 0.87 | MAPT (0.60) | MAPTLMNAKMT2AKDM4EALDH1A1 | |
| SCHEMBL528238 | 0.86 | MAPT (0.59) | MAPTLMNAKMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |