Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 5/20 | 0.55 |
| ▸ | MMP2 | P08253 | 7/20 | 0.44 |
| ▸ | MMP8 | P22894 | 7/20 | 0.44 |
| ▸ | MMP12 | P39900 | 7/20 | 0.44 |
| ▸ | MMP13 | P45452 | 7/20 | 0.44 |
| ▸ | MMP14 | P50281 | 7/20 | 0.44 |
| ▸ | MMP16 | P51512 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 6/20 | 0.41 |
| ▸ | MMP1 | P03956 | 4/20 | 0.41 |
| ▸ | MMP3 | P08254 | 4/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5568656 | 0.90 | HTR6 (0.44) | HTR6MMP2MMP8MMP12MMP13 | |
| SCHEMBL6609387 | 0.86 | KMT2A (0.56) | HTR6ALDH1A1PKMMEN1KMT2A | |
| SCHEMBL702691 | 0.84 | HTR6 (0.57) | HTR6MMP2MMP8MMP12MMP13 | |
| SCHEMBL5281915 | 0.84 | HTR6 (0.48) | HTR6MMP2MMP8MMP12MMP13 | |
| SCHEMBL5283947 | 0.83 | ADRA1A (0.47) | KDM4EGAAALDH1A1HPGDCA12 | |
| SCHEMBL9023668 | 0.82 | CA1 (0.56) | CA12CA1CA2CA9CA14 | |
| SCHEMBL699183 | 0.78 | HTR6 (0.50) | HTR6MMP2MMP8MMP12MMP13 | |
| SCHEMBL6610741 | 0.73 | GUSB (0.49) | KDM4EGAAALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL10893891 | 0.73 | HTR6 (0.64) | HTR6KDM4EALDH1A1HPGDPKM | |
| SCHEMBL10991718 | 0.73 | HTR6 (0.62) | HTR6MMP2MMP8MMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | HTR6 3695/4885MMP2 1558/4885MMP8 387/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.