SCHEMBL423302

SCHEMBL423302

Brc1ccccc1Cc1ccccc1

nearest known ligand 0.56

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 1/20 0.56
TAAR1 Q96RJ0 3/20 0.54
CALM1 P0DP23 1/20 0.52
IDO1 P14902 2/20 0.52
BCL2 P10415 1/20 0.48
BCL2L1 Q07817 1/20 0.48
CTRC Q99895 1/20 0.47
HPGD P15428 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
AOC3 Q16853 1/20 0.44
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzene SCHEMBL28195073 1.00 HTR2A (0.56) HTR2ATAAR1CALM1IDO1BCL2
Fluoride SCHEMBL27939369 0.98 HTR2A (0.54) HTR2ATAAR1CALM1IDO1BCL2
SCHEMBL4853233 0.98 HTR2A (0.54) HTR2ATAAR1CALM1IDO1BCL2
Boric Acid SCHEMBL28279493 0.91 HTR2A (0.48) HTR2ATAAR1CALM1IDO1BCL2
SCHEMBL28517240 0.91 HTR2A (0.48) HTR2ATAAR1CALM1IDO1BCL2
SCHEMBL25625114 0.87 TAAR1 (0.50) HTR2ATAAR1IDO1
SCHEMBL31152647 0.84 CALM1 (0.46) HTR2ATAAR1CALM1IDO1BCL2
SCHEMBL28025161 0.84 CALM1 (0.46) HTR2ATAAR1CALM1IDO1BCL2
SCHEMBL29930048 0.84 TAAR1 (0.64) TAAR1IDO1
SCHEMBL8703610 0.84 TAAR1 (0.64) TAAR1IDO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103435801-A Silver chloride/porous aromatic frame composite material and preparation method thereof SUZHOU NAAI PURIFYING SCIENCE & TECHNOLOGY CO LTD 2013-12-11 CN claimed
US-12635404-B2 Organometallic compound and light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2026-05-19 US disclosed
US-20240182463-A1 SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG SHIONOGI & CO., LTD. (JP) 2024-06-06 US disclosed
US-20230158039-A1 BROMODOMAIN INHIBITORS ABBVIE INC (US) 2023-05-25 US disclosed
US-20230111588-A1 ORGANOMETALLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-13 US disclosed
CN-115707324-A Organometallic compound, light-emitting device, and electronic device 三星显示有限公司 2023-02-17 CN disclosed
US-20210236508-A1 BROMODOMAIN INHIBITORS ABBVIE INC (US) 2021-08-05 US disclosed
EP-2280983-B9 C-ARYL GLYCOSIDE COMPOUNDS FOR THE TREATMENT OF DIABETES AND OBESITY TFCHEM (FR) 2021-06-09 EP disclosed
CN-107635970-B Benzimidazolone and benzothiazolone compounds and their use as AMPA receptor modulators 詹森药业有限公司 2021-03-12 CN disclosed
US-20200339565-A1 PRODRUG SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE SHIONOGI & CO., LTD. (JP) 2020-10-29 US disclosed
EP-0063793-A2 (Arylmethyl)aryl-amino-cyclohexanols, -cyclohexanes, -cyclohexenes and intermediates thereof, a process for preparing the same and their use as medicaments HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1982-11-03 EP disclosed
US-4313959-A (Arylmethyl)phenyl-aminocyclohexanols, cyclohexenes and intermediates thereof HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1982-02-02 US disclosed
US-4311703-A PYRROLIDINE AND PIPERIDINE DERIVATIVES AMERICAN HOECHST CORPORATION (US) 1982-01-19 US disclosed
US-4301292-A 1-[2-(4,5-Dihydro-4,4-dialkyl-2-oxazolyl)phenyl]-4-(dialkylamino)cyclohexanol HOECHST-ROUSSEL PHARMACEUTICALS, INCORPORATED (US) 1981-11-17 US disclosed
US-4292245-A 3'-Phenylspiro[cyclohexane-1,1'(3'H)-isobenzofuran]-4-one HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1981-09-29 US disclosed
US-4292243-A 3\"-Phenyldispiro[1,3-dioxolane-2,4'-cyclohexane-1',1\"-(3\"H)-isobenzofuran] HOECHST ROUSSEL PHARMACEUTICALS INCORPORATED (US) 1981-09-29 US disclosed
US-4290958-A Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1981-09-22 US disclosed
US-4288623-A 1-Aryl-4-amino-cyclohexan-1-ols HOECHST-ROUSSEL PHARMACEUTICALS INC. (US) 1981-09-08 US disclosed
US-4263317-A Spiro[cyclohexane-1,1'(3'H)-isobenzofuran]s HOECHST-ROUSSEL PHARMACEUTICALS, INC. (US) 1981-04-21 US disclosed
US-4241071-A Antidepressant (α-phenyl-2-tolyl)azacycloalkanes AMERICAN HOECHST CORPORATION (US) 1980-12-23 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240182463-A1 SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PRODRUG PREP, UNG, DPP4 HTR2A 3244/4885TAAR1 4505/4885CALM1 3822/4885
US-20230111588-A1 ORGANOMETALLIC COMPOUND AND LIGHT-EMITTING DEVICE INCLUDING THE SAME SOD1, AP1M1, GPS1 HTR2A 4859/4885TAAR1 1963/4885CALM1 4316/4885
US-20230158039-A1 BROMODOMAIN INHIBITORS BRD4, BRD1, BRD3 HTR2A 2225/4885TAAR1 577/4885CALM1 749/4885
US-20200339565-A1 PRODRUG SUBSTITUTED POLYCYCLIC CARBAMOYL PYRIDONE DERIVATIVE PREP, UNG, DPP4 HTR2A 3231/4885TAAR1 4460/4885CALM1 3823/4885
US-12635404-B2 Organometallic compound and light-emitting device including the same SOD1, GPS1, SLC39A11 HTR2A 4867/4885TAAR1 2787/4885CALM1 4374/4885
US-20210236508-A1 BROMODOMAIN INHIBITORS BRD4, BRD1, BRD3 HTR2A 2225/4885TAAR1 577/4885CALM1 749/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.