Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 4/20 | 0.45 |
| ▸ | CA9 | Q16790 | 3/20 | 0.45 |
| ▸ | CA12 | O43570 | 2/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | MMP8 | P22894 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28505067 | 0.78 | KMT2A (0.51) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL5281607 | 0.76 | KMT2A (0.47) | KMT2AMEN1SLC1A3SLC1A2SLC1A1 | |
| Phenylalanine Methyl Ester SCHEMBL9356083 | 0.75 | SLC7A5 (0.56) | KMT2AMEN1CA2CA9CA12 | |
| Phenylalanine Methyl Ester SCHEMBL9301524 | 0.75 | SLC7A5 (0.56) | KMT2AMEN1CA2CA9CA12 | |
| Phenylalanine Methyl Ester SCHEMBL4996192 | 0.75 | SLC7A5 (0.56) | KMT2AMEN1CA2CA9CA12 | |
| SCHEMBL8349195 | 0.74 | SLC1A3 (0.52) | KMT2AMEN1F2PRSS1PRSS2 | |
| SCHEMBL6635150 | 0.74 | SLC1A3 (0.52) | KMT2AMEN1F2PRSS1PRSS2 | |
| Phenylalanine Methyl Ester SCHEMBL74887 | 0.74 | SLC7A5 (0.63) | KMT2AMEN1ANPEPLTA4H | |
| Phenylalanine Methyl Ester SCHEMBL186022 | 0.74 | SLC7A5 (0.63) | KMT2AMEN1ANPEPLTA4H | |
| Phenylalanine Methyl Ester SCHEMBL74888 | 0.74 | SLC7A5 (0.63) | KMT2AMEN1ANPEPLTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007001335-A2 | RAMOPLANIN DERIVATIVES POSSESSING ANTIBACTERIAL ACTIVITY | VICURON PHARMACEUTICALS INC. (US) | 2007-01-04 | — | — | WO | disclosed |
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | VICURON PHARMACEUTICALS INC. (US) | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211603-A1 | Ramoplanin derivatives possessing antibacterial activity | CLSPN, LMAN2, RPN2 | KMT2A 4422/4885MEN1 2853/4885F2 4483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.