Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 2/20 | 0.51 |
| ▸ | CES2 | O00748 | 3/20 | 0.46 |
| ▸ | CES1 | P23141 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5286421 | 1.00 | DHODH (0.51) | DHODHCES2CES1KMT2AMEN1 | |
| SCHEMBL14581582 | 1.00 | DHODH (0.51) | DHODHCES2CES1KMT2AMEN1 | |
| SCHEMBL995358 | 0.88 | ALDH1A1 (0.58) | DHODHCES2CES1KMT2AMEN1 | |
| SCHEMBL995357 | 0.88 | ALDH1A1 (0.58) | DHODHCES2CES1KMT2AMEN1 | |
| SCHEMBL5263495 | 0.88 | ALDH1A1 (0.58) | DHODHCES2CES1KMT2AMEN1 | |
| SCHEMBL16973949 | 0.86 | CES2 (0.47) | DHODHCES2CES1KMT2AMEN1 | |
| SCHEMBL16973951 | 0.86 | CES2 (0.47) | DHODHCES2CES1KMT2AMEN1 | |
| SCHEMBL9382912 | 0.83 | CES1 (0.49) | CES2CES1KMT2AMEN1MAPT | |
| SCHEMBL9382917 | 0.83 | CES1 (0.49) | CES2CES1KMT2AMEN1MAPT | |
| SCHEMBL12610982 | 0.80 | CES2 (0.49) | DHODHCES2CES1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032522-A1 | Antiviral agents | VIROBAY, INC. | 2007-02-08 | — | — | US | disclosed |
| WO-2007005779-A2 | ANTIVIRAL AGENTS | VIROBAY, INC. (US) | 2007-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032522-A1 | Antiviral agents | MAVS, HAVCR2, EIF2AK2 | DHODH 336/4885CES2 593/4885CES1 306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.