Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | PTGES | O14684 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528691 | 0.86 | SMN1; SMN2 (0.51) | SMN1; SMN2KCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL528058 | 0.83 | MEN1 (0.67) | SMN1; SMN2KCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL529360 | 0.83 | LMNA (0.67) | SMN1; SMN2KCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL29873731 | 0.82 | SMN1; SMN2 (0.54) | SMN1; SMN2KCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL3456193 | 0.81 | SMN1; SMN2 (0.77) | SMN1; SMN2KCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL529287 | 0.81 | KMT2A (0.64) | SMN1; SMN2ALDH1A1LMNAMAPTHTT | |
| SCHEMBL528449 | 0.80 | ALDH1A1 (0.67) | SMN1; SMN2KCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL528383 | 0.80 | NPSR1 (0.65) | SMN1; SMN2KCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL528077 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2KCNH2ALDH1A1LMNAMAPT | |
| SCHEMBL528714 | 0.79 | SMN1; SMN2 (0.57) | SMN1; SMN2KCNH2ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |