Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528338 | 0.91 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL529111 | 0.90 | MAPT (0.64) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL529488 | 0.87 | ALDH1A1 (0.63) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL528449 | 0.87 | ALDH1A1 (0.67) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL528208 | 0.84 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL529319 | 0.84 | LMNA (0.58) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL529121 | 0.84 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL528645 | 0.83 | ALDH1A1 (0.64) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL528988 | 0.83 | ALDH1A1 (0.62) | MAPTALDH1A1KDM4EHPGDHTT | |
| SCHEMBL527892 | 0.83 | MAPT (0.73) | MAPTALDH1A1KDM4EHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012014127-A1 | 5-LIPOXYGENASE INHIBITORS | RANBAXY LABORATORIES LIMITED (IN) | 2012-02-02 | — | — | WO | disclosed |