Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.43 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | GALR3 | O60755 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15272684 | 0.98 | NPC1 (0.44) | NPC1RAB9AHTTALDH1A1LMNA | |
| SCHEMBL8198312 | 0.94 | MEN1 (0.39) | NPC1RAB9AHTTALDH1A1LMNA | |
| SCHEMBL5268111 | 0.86 | — | — | |
| SCHEMBL7472670 | 0.77 | — | — | |
| SCHEMBL2586279 | 0.77 | NPC1 (0.47) | NPC1RAB9AHTTALDH1A1LMNA | |
| SCHEMBL11500425 | 0.72 | SMN1; SMN2 (0.54) | NPC1RAB9AHTTALDH1A1LMNA | |
| SCHEMBL7837324 | 0.70 | DUT (0.56) | — | |
| SCHEMBL17372138 | 0.69 | DUT (0.55) | CYP1A2CYP2C19 | |
| SCHEMBL3434118 | 0.68 | ALDH1A1 (0.36) | ALDH1A1HSP90AA1MAPTFAAHTP53 | |
| SCHEMBL16671885 | 0.68 | HTT (0.41) | HTTCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115028582-B | Preparation method of N-aryl pyrazole medicine E-52862 and product thereof | 曲靖师范学院 | 2024-04-12 | — | — | CN | claimed |
| EP-0082415-A1 | Heavy metal complex azo compounds soluble in water, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-06-29 | — | — | EP | claimed |
| US-4061498-A | SILVER HALIDE EMULSION | AGFA-GEVAERT, N.V. (BE) | 1977-12-06 | — | — | US | claimed |
| CN-114874144-B | Process for preparing 4-bromo-N-arylpyrazole compound | 曲靖师范学院 | 2024-07-05 | — | — | CN | disclosed |
| CN-115028582-B | Preparation method of N-aryl pyrazole medicine E-52862 and product thereof | 曲靖师范学院 | 2024-04-12 | — | — | CN | disclosed |
| CN-115028582-B | Preparation method of N-aryl pyrazole medicine E-52862 and product thereof | 曲靖师范学院 | 2024-04-12 | — | — | CN | disclosed |
| US-9035070-B2 | Process for the preparation of 1-aryl-pyrazol-3-one intermediates useful in the synthesis of sigma receptors inhibitors | Esteve Química, S.A. (ES) | 2015-05-19 | — | — | US | disclosed |
| US-9035070-B2 | Process for the preparation of 1-aryl-pyrazol-3-one intermediates useful in the synthesis of sigma receptors inhibitors | Esteve Química, S.A. (ES) | 2015-05-19 | — | — | US | disclosed |
| US-9035070-B2 | Process for the preparation of 1-aryl-pyrazol-3-one intermediates useful in the synthesis of sigma receptors inhibitors | Esteve Química, S.A. (ES) | 2015-05-19 | — | — | US | disclosed |
| CN-103038208-B | Process for the preparation of 1-aryl-pyrazol-3-one intermediates useful in the synthesis of sigma receptors inhibitors | ESTEVE QUIMICA SA | 2015-05-06 | — | — | CN | disclosed |
| CN-103038208-B | Process for the preparation of 1-aryl-pyrazol-3-one intermediates useful in the synthesis of sigma receptors inhibitors | ESTEVE QUIMICA SA | 2015-05-06 | — | — | CN | disclosed |
| EP-0082415-A1 | Heavy metal complex azo compounds soluble in water, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-06-29 | — | — | EP | disclosed |
| EP-0082415-A1 | Heavy metal complex azo compounds soluble in water, process for their preparation and their use as dyestuffs | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-06-29 | — | — | EP | disclosed |
| EP-0011693-A1 | N-trifluoromethane-sulfonylaminophenyl-substituted N-heterocycles, their preparation, compositions containing them and their use in regulating plant growth | CIBA-GEIGY AG (CH) | 1980-06-11 | — | — | EP | disclosed |
| US-4123281-A | Photographic silver halide color material containing fast-acting hardener and 2-pyrazolin-5-one coupler precursors | AGFA-GEVAERT N.V. (BE) | 1978-10-31 | — | — | US | disclosed |
| US-4061498-A | SILVER HALIDE EMULSION | AGFA-GEVAERT, N.V. (BE) | 1977-12-06 | — | — | US | disclosed |
| US-4061498-A | SILVER HALIDE EMULSION | AGFA-GEVAERT, N.V. (BE) | 1977-12-06 | — | — | US | disclosed |
| US-4056410-A | PROCESS FOR PREPARING ACICULAR IRON POWDERS CONTAINING TITANIUM AND TIN, AND THE RESULTING POWDERS WHEN SO PREPARED | MONTEDISON, S.P.A. (IT) | 1977-11-01 | — | — | US | disclosed |
| US-4054718-A | Heat-sensitive recording material containing a malachite green color former | CIBA-GEIGY CORPORATION (US) | 1977-10-18 | — | — | US | disclosed |
| US-3973979-A | MAGENTA DYES, SILVER HALIDE EMULSIONS | AGFA-GEVAERT, A.G. (DT) | 1976-08-10 | — | — | US | disclosed |