Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 6/20 | 0.36 |
| ▸ | RAB9A | P51151 | 6/20 | 0.36 |
| ▸ | HTT | P42858 | 5/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 2/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GALR3 | O60755 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL528762 | 0.94 | NPC1 (0.43) | NPC1RAB9AHTTLMNAAPOBEC3A | |
| SCHEMBL15272684 | 0.92 | NPC1 (0.44) | NPC1RAB9AHTTLMNAAPOBEC3A | |
| SCHEMBL5268111 | 0.88 | — | — | |
| SCHEMBL7472670 | 0.79 | — | — | |
| SCHEMBL2586279 | 0.71 | NPC1 (0.47) | NPC1RAB9AHTTLMNAAPOBEC3A | |
| SCHEMBL6864606 | 0.69 | DUT (0.57) | L3MBTL1CRBN | |
| SCHEMBL3434118 | 0.66 | ALDH1A1 (0.36) | ALDH1A1HSP90AA1MAPT | |
| SCHEMBL20261008 | 0.65 | DUT (0.34) | CRBNSMN1; SMN2 | |
| SCHEMBL11500425 | 0.65 | SMN1; SMN2 (0.54) | MEN1KMT2AL3MBTL1NPC1RAB9A | |
| SCHEMBL7837324 | 0.64 | DUT (0.56) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000034247-A2 | METHOD FOR PRODUCING PYRAZOLYLBENZOYL DERIVATIVES AND NOVEL PYRAZOLYLBENZOYL DERIVATIVES | BASF AKTIENGESELLSCHAFT (DE) | 2000-06-15 | — | — | WO | disclosed |
| US-5663365-A | Process for the preparation of pyrazolones | JAPAN HYDRAZINE CO., LTD. (JP) | 1997-09-02 | — | — | US | disclosed |