SCHEMBL5287781

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5280097	0.83	RIPK1 (0.43)	RIPK1GPR52KMT2AMEN1ALDH1A1
	SCHEMBL9565762	0.76	RIPK1 (0.51)	RIPK1GPR52KMT2AMEN1ALDH1A1
	SCHEMBL16393647	0.76	RIPK1 (0.47)	RIPK1GPR52KMT2AMEN1ALDH1A1
	SCHEMBL29836734	0.76	RIPK1 (0.51)	RIPK1GPR52KMT2AMEN1ALDH1A1
	SCHEMBL3533731	0.73	CYP2C19 (0.38)	RIPK1KMT2AALDH1A1CYP2C19HIF1A
	SCHEMBL11970972	0.73	RIPK1 (0.47)	RIPK1ALDH1A1CYP2C19LMNATAAR1
	SCHEMBL4411791	0.73	CA12 (0.47)	GPR52KMT2AMEN1ALDH1A1KDM4E
	SCHEMBL15637806	0.72	RIPK1 (0.48)	RIPK1GPR52KMT2AMEN1ALDH1A1
	SCHEMBL5925975	0.72	RIPK1 (0.41)	RIPK1GPR52KMT2AMEN1ALDH1A1
	SCHEMBL31117942	0.72	TAAR1 (0.50)	RIPK1ALDH1A1CYP2C19LMNATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.