Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | CTSK | P43235 | 1/20 | 0.41 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9565762 | 1.00 | RIPK1 (0.51) | RIPK1LMNAKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL15983796 | 0.86 | LMNA (0.49) | RIPK1LMNAKDM4EL3MBTL1SLC22A12 | |
| SCHEMBL16393647 | 0.85 | RIPK1 (0.47) | RIPK1LMNAKDM4EALDH1A1CTSS | |
| SCHEMBL19182690 | 0.83 | GABRA1 (0.48) | RIPK1LMNAKDM4EL3MBTL1SLC22A12 | |
| SCHEMBL24140655 | 0.80 | RIPK1 (0.47) | RIPK1ALDH1A1CTSSCTSKPOLB | |
| SCHEMBL1114878 | 0.79 | AKR1B1 (0.53) | LMNAKDM4EL3MBTL1POLBTAAR1 | |
| SCHEMBL4458475 | 0.79 | KDM4E (0.51) | LMNAKDM4EL3MBTL1ALDH1A1POLB | |
| SCHEMBL3093272 | 0.79 | RIPK1 (0.49) | RIPK1LMNAKDM4EALDH1A1CTSS | |
| SCHEMBL12802659 | 0.78 | RIPK1 (0.49) | RIPK1ALDH1A1POLBHPGDKMT2A | |
| SCHEMBL22175384 | 0.78 | RIPK1 (0.43) | RIPK1LMNAKDM4EALDH1A1CTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114891034-A | TML type trigger molecule and preparation method and application thereof | 闽都创新实验室 | 2022-08-12 | — | — | CN | disclosed |