Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | CA12 | O43570 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CTSG | P08311 | 1/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6454098 | 0.81 | SLC22A2 (0.36) | KMT2AKDM4EALDH1A1HSD11B1MEN1 | |
| Toluene SCHEMBL4224326 | 0.80 | CA12 (0.43) | MAPTKDM4ECA12CA9CA2 | |
| SCHEMBL5745107 | 0.80 | CA12 (0.37) | MAPTKMT2AKDM4ECA12CA9 | |
| SCHEMBL57931 | 0.78 | TDP1 (0.45) | MAPTKMT2AKDM4ECA12CA9 | |
| SCHEMBL6915057 | 0.78 | HSD11B1 (0.42) | HTR2AHTR2CMAPTKMT2AKDM4E | |
| SCHEMBL5399285 | 0.78 | HSD11B1 (0.42) | HTR2AHTR2CMAPTKMT2AKDM4E | |
| SCHEMBL135009 | 0.78 | HSD11B1 (0.42) | HTR2AHTR2CMAPTKMT2AKDM4E | |
| SCHEMBL20533883 | 0.78 | HSD11B1 (0.42) | HTR2AHTR2CMAPTKMT2AKDM4E | |
| SCHEMBL20658918 | 0.78 | HSD11B1 (0.42) | HTR2AHTR2CMAPTKMT2AKDM4E | |
| SCHEMBL16034284 | 0.78 | TDP1 (0.45) | MAPTKMT2AKDM4ECA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2598552-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | University Of Akron (US) | 2013-06-05 | — | — | EP | claimed |
| WO-2012015481-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | UNIVERSITY OF AKRON (US) | 2012-02-02 | — | — | WO | claimed |
| US-10023689-B2 | Functional biodegradable polymers | THE UNIVERSITY OF AKRON | 2018-07-17 | — | — | US | disclosed |
| US-20160229952-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | NATIONAL SCIENCE FOUNDATION | 2016-08-11 | — | — | US | disclosed |
| US-20130184429-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | THE UNIVERSITY OF AKRON (US) | 2013-07-18 | — | — | US | disclosed |
| EP-2598552-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | University Of Akron (US) | 2013-06-05 | — | — | EP | disclosed |
| WO-2012015481-A1 | FUNCTIONAL BIODEGRADABLE POLYMERS | UNIVERSITY OF AKRON (US) | 2012-02-02 | — | — | WO | disclosed |
| WO-2006023130-A2 | BIODEGRADABLE CONTROLLED RELEASE BIOACTIVE AGENT DELIVERY DEVICE | SURMODICS, INC. (US) | 2006-03-02 | — | — | WO | disclosed |
| US-20060034891-A1 | Biodegradable controlled release bioactive agent delivery device | SURMODICS MD, LLC | 2006-02-16 | — | — | US | disclosed |
| WO-2004039335-A2 | POLYMER COMPOSITIONS COMPRISING ANTIFIBROTIC AGENTS, AND METHODS OF TREATMENT, PHARMACEUTICAL COMPOSITIONS, AND METHODS OF PREPARATION THEREFOR | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2004-05-13 | — | — | WO | disclosed |
| US-20030186869-A1 | Polymer compositions comprising antifibrotic agents, and methods of treatment, pharmaceutical compositions, and methods of preparation therefor | POIANI GEORGE (US) | 2003-10-02 | — | — | US | disclosed |
| EP-0931119-B1 | CHIRAL COMPOUNDS WITH LIQUID CRYSTALLINE NATURE AND FERROELECTRIC LIQUID CRYSTAL DEVICE ADOPTING THE SAME | SAMSUNG DISPLAY DEVICES CO LTD (KR) | 2001-12-05 | — | — | EP | disclosed |
| EP-0931119-A1 | CHIRAL COMPOUNDS WITH LIQUID CRYSTALLINE NATURE AND FERROELECTRIC LIQUID CRYSTAL DEVICE ADOPTING THE SAME | SAMSUNG DISPLAY DEVICES CO., LTD. (KR) | 1999-07-28 | — | — | EP | disclosed |
| WO-1998014529-A1 | CHIRAL COMPOUNDS WITH LIQUID CRYSTALLINE NATURE AND FERROELECTRIC LIQUID CRYSTAL DEVICE ADOPTING THE SAME | SAMSUNG DISPLAY DEVICES CO., LTD. (KR) | 1998-04-09 | — | — | WO | disclosed |
| US-5720950-A | ALKOXYLATED PROLINE ANALOG | UNIVERSITY OF MEDICINE & DENTISTRY OF NEW JERSEY (US) | 1998-02-24 | — | — | US | disclosed |
| US-5660822-A | A PROLINE ANALOG LINKED TO A POLYOXYALKYLENE ETHER THROUGH A SPACER COMPOUND SUCH AS LYSINE; CONTROLLING THE PROLIFERATION OF COLLAGEN; TIME-RELEASE AGENTS; NONTOXIC | UNIVERSITY OF MEDICINE & DENTISTRY OF N.J. (US) | 1997-08-26 | — | — | US | disclosed |
| US-5455027-A | Drug delivery | ENZON, INC. (US) | 1995-10-03 | — | — | US | disclosed |
| US-5372807-A | Proline analogs administered to inhibit collagen accumulation | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 1994-12-13 | — | — | US | disclosed |
| US-5219564-A | Containing pendant carboxylic acid groups | ENZON, INC. (US) | 1993-06-15 | — | — | US | disclosed |
| WO-1992000748-A1 | POLY(ALKYLENE OXIDE) AMINO ACID COPOLYMERS AND DRUG CARRIERS AND CHARGED COPOLYMERS BASED THEREON | ENZON, INC. (US) | 1992-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186869-A1 | Polymer compositions comprising antifibrotic agents, and methods of treatment, pharmaceutical compositions, and methods of preparation therefor | PDF, DHPS, FIBP | HTR2A 4471/4885HTR2C 4212/4885MAPT 3218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.