Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475583 | 1.00 | KDM4E (0.57) | KDM4ENPC1RAB9AHRH3HPGD | |
| SCHEMBL5287827 | 1.00 | KDM4E (0.57) | KDM4ENPC1RAB9AHRH3HPGD | |
| SCHEMBL1472922 | 0.89 | KDM4E (0.52) | KDM4ENPC1RAB9AHRH3HPGD | |
| SCHEMBL5294746 | 0.84 | KDM4E (0.51) | KDM4ENPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL8283237 | 0.81 | KDM4E (0.58) | KDM4ENPC1RAB9AMAPTL3MBTL1 | |
| SCHEMBL5289807 | 0.80 | HRH3 (0.51) | HRH3HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL5295906 | 0.80 | HRH3 (0.51) | HRH3HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL1474034 | 0.80 | HRH3 (0.51) | HRH3HPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL27669293 | 0.79 | EDNRA (0.54) | KDM4ENPC1RAB9AHRH3 | |
| SCHEMBL1473531 | 0.75 | KDM4E (0.47) | KDM4ENPC1RAB9AHPGDMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006715-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-01-18 | — | — | WO | claimed |
| WO-2007006715-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-01-18 | — | — | WO | disclosed |