Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.44 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.41 |
| ▸ | P2RX2 | Q9UBL9 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1473531 | 0.91 | KDM4E (0.47) | KDM4EEPHA2NPC1RAB9AERBB2 | |
| SCHEMBL8251140 | 0.91 | KDM4E (0.47) | KDM4EEPHA2NPC1RAB9AERBB2 | |
| SCHEMBL1475583 | 0.84 | KDM4E (0.57) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5287827 | 0.84 | KDM4E (0.57) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5288124 | 0.84 | KDM4E (0.57) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9214625 | 0.80 | KDM4E (0.56) | KDM4EMAPT | |
| SCHEMBL1852171 | 0.80 | PDK1 (0.51) | EPHA2ERBB2EPHB4PDK1P2RX3 | |
| SCHEMBL5294751 | 0.79 | KDM4E (0.51) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9210866 | 0.78 | KDM4E (0.49) | KDM4EEPHA2ERBB2EPHB4PDK1 | |
| SCHEMBL5297191 | 0.78 | EPHA2 (0.43) | EPHA2ERBB2EPHB4PDK1CSF1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007006714-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-01-18 | — | — | WO | disclosed |
| WO-2007006715-A1 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2007-01-18 | — | — | WO | disclosed |