Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1475583 | 0.81 | KDM4E (0.57) | KDM4ENPC1RAB9AMCL1ALDH1A1 | |
| SCHEMBL5288124 | 0.81 | KDM4E (0.57) | KDM4ENPC1RAB9AMCL1ALDH1A1 | |
| SCHEMBL5287827 | 0.81 | KDM4E (0.57) | KDM4ENPC1RAB9AMCL1ALDH1A1 | |
| SCHEMBL9211102 | 0.78 | MAOB (0.55) | KDM4ERAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9217447 | 0.77 | MAOB (0.57) | KDM4ERAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9213168 | 0.77 | MAOB (0.57) | KDM4ERAB9AALDH1A1 | |
| Hydrochloric Acid SCHEMBL9211581 | 0.77 | MAOB (0.57) | KDM4ERAB9AALDH1A1 | |
| SCHEMBL5294746 | 0.76 | KDM4E (0.51) | KDM4ENPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9218485 | 0.74 | ALDH1A1 (0.54) | KDM4ENPC1RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL28209632 | 0.74 | KDM4E (0.53) | KDM4ENPC1RAB9AALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005066180-A9 | CYSTEINE PROTEASE INHIBITORS | MEDIVIR AB (SE) | 2008-09-25 | — | — | WO | disclosed |