Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10884613 | 0.84 | MAPT (0.60) | ALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL23612374 | 0.80 | ALDH1A1 (0.64) | ALDH1A1GLAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL30061252 | 0.80 | ALDH1A1 (0.64) | ALDH1A1GLAMAPTSMN1; SMN2MEN1 | |
| SCHEMBL877985 | 0.80 | FFAR1 (0.57) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL15426812 | 0.79 | MAPT (0.55) | ALDH1A1GLAMAPTSMN1; SMN2KMT2A | |
| SCHEMBL7224442 | 0.78 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11212940 | 0.78 | ALDH1A1 (0.51) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL11212945 | 0.78 | SMN1; SMN2 (0.58) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL8261330 | 0.78 | ALDH1A1 (0.48) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL6239095 | 0.78 | MAPT (0.54) | ALDH1A1GLAMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3187488-B1 | NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVE AND USE THEREOF | CJ HEALTHCARE CORP (KR) | 2020-02-19 | — | — | EP | disclosed |
| EP-3187488-B1 | NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVE AND USE THEREOF | CJ HEALTHCARE CORP (KR) | 2020-02-19 | — | — | EP | disclosed |
| CN-107155325-B | Novel amino-phenyl-sulfonyl-acetic ester derivative and application thereof | CJ医药健康株式会社 | 2019-08-06 | — | — | CN | disclosed |
| US-20170247320-A1 | NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVES AND USE THEREOF | CJ HEALTHCARE CORPORATION (KR) | 2017-08-31 | — | — | US | disclosed |
| US-20170247320-A1 | NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVES AND USE THEREOF | CJ HEALTHCARE CORPORATION (KR) | 2017-08-31 | — | — | US | disclosed |
| US-20170247320-A1 | NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVES AND USE THEREOF | CJ HEALTHCARE CORPORATION (KR) | 2017-08-31 | — | — | US | disclosed |
| EP-3187488-A1 | NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVE AND USE THEREOF | CJ Healthcare Corporation (KR) | 2017-07-05 | — | — | EP | disclosed |
| EP-3187488-A1 | NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVE AND USE THEREOF | CJ Healthcare Corporation (KR) | 2017-07-05 | — | — | EP | disclosed |
| WO-2016032120-A1 | NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVE AND USE THEREOF | 씨제이헬스케어 주식회사 | 2016-03-03 | — | — | WO | disclosed |
| CN-103228634-A | Matrix metalloproteinase inhibitors | RANBAXY LAB LTD | 2013-07-31 | — | — | CN | disclosed |
| EP-1863804-A1 | INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2007-12-12 | — | — | EP | disclosed |
| US-20060264415-A1 | Inhibitors of histone deacetylase | METHYLGENE INC. | 2006-11-23 | — | — | US | disclosed |
| WO-2006102760-A1 | INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264415-A1 | Inhibitors of histone deacetylase | HDAC1, HDAC3, HDAC11 | ALDH1A1 781/4885GLA 372/4885MAPT 3848/4885 |
| US-20170247320-A1 | NOVEL AMINO-PHENYL-SULFONYL-ACETATE DERIVATIVES AND USE THEREOF | SLC5A2, SLC5A1, IAPP | ALDH1A1 2267/4885GLA 571/4885MAPT 2645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.